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Luca Penso DolfinLP

Luca Penso Dolfin

Bioinformatician

€340/day
Berlin, DE
8-15 years

Average response time: 1 hour

About Luca

I hold a Master degree in Evoluionary Biology and a PhD in Computational Biology.
With approximately 10 years of experience in bioinformatic research, I can offer a sound knowledge of biology and the analysis of high-thoughput sequencing data.

In the past, I worked in both academic and industry research environments, and I got used to interdisciplinary, highly collaborative work.



I have a long term experience in the following:
- analysis and interpretation of various NGS data types (DNA-seq, bulk RNA-seq, single cell RNA-seq)
- conceptualization and development of robust bioinformatics pipelines
- summary and visualisation of biological data
- design of experiments to validate computational predictions

Additionally, I have a solid understanding of machine learning methods, including code development for model training and validation.


  • English

    Native or bilingual

Remote only
Primarily works remotely

Experience

  • Silence Therapeutics GmbH,
    BIOINFORMATICIAN
    January 2021 - August 2025 (4 years and 8 months)
    Berlin, Germany
    • Main tasks and responsibilities: RNA-seq analyses (QC, differential gene expression); risk assessment of candidate molecules; backing up data in the cloud; development of bioinformatic workflows and machine learning models to identify RNAi mechanisms; regular presentations of results
  • Deutsches Krebsforschungszentrum (DKFZ),
    COMPUTATIONAL BIOLOGIST
    January 2019 - January 2020 (1 year)
    69 Heidelberg, Germany
    • Focus: somatic evolution and gene expression variability at the single-cell level
    • Main tasks and responsibilities: single-cell RNA-seq analyses; development of bioinformatic workflows to detect somatic variants; differential gene expression; supervise students; regular presentations of results
  • Earlham Institute,
    COMPUTATIONAL BIOLOGIST
    January 2014 - January 2019 (5 years)
    Norwich, UK
    • Focus: microRNA annotation and evolution in mammals
    • Side project: identification of structural variation and gene regulatory networks in African cichlids
    • Main tasks and responsibilities: microRNA annotation and profiling; microRNA target prediction; identification of structural variants from paired-end reads; differential gene expression; gene set enrichment; sequence clustering; orthology analyses; read and whole genome alignments; database search; regular presentations of results

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