About Luca
English
Native or bilingual
Experience
- Silence Therapeutics GmbH,BIOINFORMATICIANJanuary 2021 - August 2025 (4 years and 8 months)Berlin, Germany• Main tasks and responsibilities: RNA-seq analyses (QC, differential gene expression); risk assessment of candidate molecules; backing up data in the cloud; development of bioinformatic workflows and machine learning models to identify RNAi mechanisms; regular presentations of results
- Deutsches Krebsforschungszentrum (DKFZ),COMPUTATIONAL BIOLOGISTJanuary 2019 - January 2020 (1 year)69 Heidelberg, Germany• Focus: somatic evolution and gene expression variability at the single-cell level• Main tasks and responsibilities: single-cell RNA-seq analyses; development of bioinformatic workflows to detect somatic variants; differential gene expression; supervise students; regular presentations of results
- Earlham Institute,COMPUTATIONAL BIOLOGISTJanuary 2014 - January 2019 (5 years)Norwich, UK• Focus: microRNA annotation and evolution in mammals• Side project: identification of structural variation and gene regulatory networks in African cichlids• Main tasks and responsibilities: microRNA annotation and profiling; microRNA target prediction; identification of structural variants from paired-end reads; differential gene expression; gene set enrichment; sequence clustering; orthology analyses; read and whole genome alignments; database search; regular presentations of results
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Skill set
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