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Léa MammriLM

Léa Mammri

Biochemistry & Biotechnology Specialist

€750/day
Paris, FR
3-7 years

Average response time: 1 hour

Freelancer profile translated to English.
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About Léa

Consultant in biochemistry and biotechnology, I offer my scientific and technical expertise to support companies and laboratories in their research and development projects. A specialist in protein biochemistry, I have solid experience in the expression and purification of recombinant proteins, as well as in molecular biology and structural biology.
As head of a purification platform within a leading academic institute, I also have a lab manager role, combining technical mastery with operational management. As part of my doctoral project, I am conducting cutting-edge research on the activation mechanism of the γ-TuRC protein complex, using approaches from cell biology, biochemistry, and microscopy (cryo-EM and TIRF microscopy).
My experience covers experimental design, complex data analysis, scientific publication writing, and presentation of results at international conferences. Accustomed to working in international collaboration, I support my partners on issues ranging from the optimization of experimental protocols to the structural interpretation of proteins and biological complexes.

✅ Key areas of expertise:
– Protein biochemistry & molecular biology
– Expression & purification of recombinant proteins
– Management of scientific platforms and projects
– Consulting, writing, and scientific communication
  • French

    Native or bilingual

  • English

    Fluent

  • Spanish

    Conversational

  • Dutch

    Basic

Remote only
Primarily works remotely

Experience

  • CNRS
    Assistant Engineer in Protein Biochemistry
    RESEARCH
    February 2016 - January 2021 (4 years and 11 months)
    Montpellier, France
    Member of the "Structure and functions of biomolecules by NMR" team led by Christian Roumestand and Nathalie Declerck at the Center for Structural Biochemistry in Montpellier (CNRS).

    Responsible for the expression, purification, and biophysical characterization of proteins for the team.

    Molecular biology: cloning, sequencing analysis.
    Microbiology: protein expression in prokaryotic and eukaryotic systems, isotopic labeling for NMR and crystallography.
    Cell biology: baculovirus production using Sf9 cells, transfection, work in an L2 level laboratory.
    Crystallography: screening of sparse matrices, refinement, and seeding using the Mosquito liquid handling robot. Use of the Formulatrix Rock Imager robot.
    Biophysical characterization: SEC-MALS, CD, TSA, and ITC.

    Supervision of interns (bachelor's and master's).
    Laboratory management: orders and inventory management.
    Protein Biochemistry Molecular Biology Structural Biology Lab Management Teamwork
  • EMBL
    Crystallography Platform Engineer
    BIOTECH
    February 2021 - February 2022 (1 year)
    Grenoble, France
    Member of the "High-Throughput X-ray Crystallography" laboratory

    - Operator on the high-throughput crystallization platform
    - Management of fragment screening campaign projects
    - Research project management
    - CrystalDirect technology enabling fully automated crystal mounting and processing
    - Optimization of crystallization conditions
    - Data collection and analysis

    Platform management: orders, inventory management


    Platform Management Innovation Strategy Structural Biology Scientific Project Management Teamwork
  • CNRS
    Biochemist Engineer
    RESEARCH
    May 2023 - Today (3 years and 1 month)
    Paris, France
    Biochemistry engineer at CNRS, I am developing my own research project on exploring the activation mechanism of the γ-TuRC complex (γ-tubulin ring complex) in Drosophila melanogaster, while providing technical and scientific support to my team's projects.

    I also oversee the operational management of the laboratory as a lab manager (orders, stocks, organization).
    Specializing in protein biochemistry, I have in-depth expertise in the expression and purification of recombinant proteins, as well as in molecular and structural biology.
    As head of the protein purification platform at the Institut Jacques Monod, I provide my expertise to other teams within the institute to help them carry out their projects.
    My skills range from conducting fundamental research projects to optimizing experimental processes, and I regularly contribute to scientific dissemination through presentations and posters at international conferences.
    Teamwork Project Management Cell Biology Genetic Engineering User Training

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Education

  • PhD in Cell and Molecular Biology
    Université de Paris Cité
    2025
  • Master's in Structural and Functional Biology
    Université Claude Bernard Lyon 1
    2023

Skill set

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